IBD
Study team
Studies
19 studies
ARES-CD – Evaluation of TulisokibartCrohn's DiseaseCrohn's DiseaseOpen for participation
A randomized, double-blind, placebo-controlled study to evaluate the efficacy and safety of Tulisokibart in patients with moderate-to-severe active Crohn's disease.
Charge-Guselkumab vs. RisankizumabCrohn's diseaseCrohn's diseaseOpen for participation
A randomized, open-label, active-controlled study comparing the efficacy and safety of guselkumab versus risankizumab in the treatment of patients with moderate-to-severe active Crohn's disease.
OMICROHN – Treatment Selection for Crohn's Disease Based on Epigenetic MarkersCrohn's DiseaseCrohn's DiseaseOpen for participation
A prospective, randomized study on treatment selection in adults with Crohn's disease, comparing the use of epigenetic markers with standard treatment.
SKYLINE-UC - Research on Long-Acting AntibodiesUlcerative ColitisUlcerative ColitisOpen for participation
A platform study investigating the safety and efficacy of multiple long-acting antibodies, both alone and in combination, for moderate-to-severe active ulcerative colitis.
Soprano – Prevention of Postoperative RecurrenceCrohn's DiseaseCrohn's DiseaseOpen for participation
A multicenter study comparing the systematic initiation of biological therapy immediately following surgical resection with the more targeted initiation of biological therapy in patients with endoscopic lesions six months after surgery.
VECTORS – Transmural HealingCrohn's DiseaseCrohn's DiseaseOpen for participation
An interventional study of personalized treatment for patients with moderate-to-severe to severe active Crohn's disease, aimed at achieving transmural healing.
CLEAR-UP: Upadacitinib for Stenosing Crohn's DiseaseCrohn's DiseaseCrohn's DiseaseStarting soon
Crohn's Disease: Longitudinal Evaluation of the Antifibrotic Response to UPadacitinib.
Empire Persistence TreatmentIBDIBDStarting soon
A comparative study of first-line and second-line treatments using data from the Belgian National IBD Registry and UR-CARE.
GA46438-Afimkibart, drug-disease interactionulcerative colitisulcerative colitisStarting soon
An open-label study to evaluate the pharmacokinetics of cytochrome P450 substrates following treatment with afimkibart in participants with moderate-to-severe active ulcerative colitis.
J6Z-MC-IIBD—Effect of Mirikizumab alone versus combination therapyulcerative colitis or Crohn's diseaseulcerative colitis or Crohn's diseaseStarting soon
A master protocol for randomized, controlled trials of multiple interventions for the treatment of adults with moderate-to-severe active ulcerative colitis or Crohn's disease
P24-960-ULTRA—Upadacitinib in Standard CareIBDIBDStarting soon
Insights into local treatment patterns and outcomes with upAdacitinib among IBD patients in Belgium.
LIFT-UC – Non-invasive monitoring of guselkumabulcerative colitisulcerative colitisStarting soon
Abdominal ultrasound and fecal calprotectin as noninvasive alternatives to endoscopy for monitoring patients with ulcerative colitis being treated with guselkumab.
NOV-ERA – Ontunisertib for fibrostenotic Crohn's diseaseCrohn's diseaseCrohn's diseaseStarting soon
A randomized, placebo-controlled, double-blind study to evaluate the efficacy and safety of Ontunisertib in patients with fibrostenosing Crohn's disease.
DUET-ENCORE – Guselkumab/Golimumab CombinationCrohn's DiseaseCrohn's DiseaseStarting soon
A randomized, double-blind, active-controlled study to evaluate the efficacy and safety of JNJ-78934804 in patients with active Crohn's disease
ALBATROS – Infliximab for Crohn's disease with fistulasCrohn's DiseaseCrohn's DiseaseStarting soon
Subcutaneous infliximab for perianal fistulizing Crohn's disease
AMARETTO – Subcutaneous Infliximab Following Prior Dose OptimizationCrohn's Disease or Ulcerative ColitisCrohn's Disease or Ulcerative ColitisClosed
A study on the use of subcutaneous infliximab following prior intravenous dose optimization in patients with Crohn's disease or ulcerative colitis.
AMETRINE 1 – RO7790121Ulcerative ColitisUlcerative ColitisClosed
A double-blind, placebo-controlled Phase III study of the efficacy and safety of induction and maintenance therapy with RO7790121 in patients with moderate-to-severe active ulcerative colitis.
OATS – FIT Diet and Biological TherapyCrohn's DiseaseCrohn's DiseaseClosed
A study on the combination of the FIT diet and biological therapy in patients with Crohn's disease.
POMEROL – Escalation of Treatment for Postoperative RecurrenceCrohn's DiseaseCrohn's DiseaseClosed
A randomized, controlled trial evaluating therapy escalation in patients with moderate postoperative recurrence of Crohn's disease.